Standard BioTools on LinkedIn: #appnote #immuneprofiling #cytometry #cellbiology (2024)

In a study of mouse embryo normal brain and glioblastoma tissues, a 44-marker neuro-oncology panel composed of the Maxpar OnDemand™ Mouse Immuno-Oncology IMC™ Panel Kit and the Maxpar Neuro Phenotyping IMC Panel Kit revealed the spatial distribution of over 40 distinct molecular markers.A Preview Mode scan using Hyperion XTi™ rapidly identified areas with high tumor and immune cell activity, which was used to identify relevant regions of interest for detailed Cell Mode investigation. Multiplex Cell Mode images using tumor- (top) and immune- (bottom) specific markers demonstrate the heterogeneity of the tumor microenvironment.Get more details on this and other applications for high-plex tissue imaging: https://lnkd.in/gwSDzSaD#lookbook #spatialbiology #neurooncology #tumorcell #immunecell #glioblastoma

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Why not do other things with your day? Hear how the automation built into CyTOF XT™ can change the way you work.Watch this and other thoughts on using CyTOF® technology: https://lnkd.in/gBYfBFzM#cytometry #labautomation

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Antimicrobial resistance is key for newly evolving environmental microbes and human pathogens. We’d like to highlight this new work from the University of Yamanashi that simultaneously quantified antibiotic resistance genes in wastewater using high-throughput qPCR to understand the relationship between #pathogens and #antibioticresistance.Read the #publication to learn how wastewater-based #epidemiology focusing on quantifying pathogens and biological markers present in wastewater is vital to informing #publichealth efforts. Microfluidics-based high-throughput qPCR successfully analyzed pathogens and ARGs in a single run, concurrently assessing 14 distinct assays.Shrestha et al. 2024: https://lnkd.in/gubV6fhZ

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A must-see session highlighting what you could be missing… See results from a direct head-to-head comparison of intracellular target resolution between #CyTOF and fluorescent cytometry. Jennifer Snyder-Cappione, PhD, discusses how CyTOF® flow cytometry can enhance understanding of the dynamics of immune responses and open new avenues for targeted therapies: https://lnkd.in/gZnuNahM#cytokines #phosphorylation #transcriptionfactors#inflammation

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Interested in new applications and platforms for single cell multiplex proteomics? Join us in San Francisco on June 17 for an early reveal of a new publication with the chapter authors themselves. Get practical advice on designing experiments with multiplexed single-cell analytical techniques and get a sneak peek into a complete guide on currently available tools. Check out who's speaking and save your seat at this complimentary event: https://lnkd.in/gX-qAvSUIntroducing the ideal reference for researchers who want to understand the variety of multiplex visualization techniques available and how to make better decisions on applying them to a biological question of interest: https://lnkd.in/gP6sBgUK #singlecell #symposium #lifesciences #education #leaders

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It’s Pride Month, and we are proud to stand together, embrace our diversity and foster an encouraging environment where people feel comfortable to be true to themselves and do their best work. Standard BioTools™ is and always will be a workplace where everyone can feel seen, heard and accepted. We are honored to continue our commitment to pursue respect and equality for all and empower our teammates to share their own pride. Let's support #Diversity #Inclusion #Equality #Innovation #Empowerment#PrideMonth is celebrated around the world from Vienna to Ibiza to Taipei to New York and everywhere in between.

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Join us for lunch at #EACR2024 to learn how spatial proteomic analysis of a #lungcancer model reveals regulatory T cells as modulators of KRAS-G12C inhibitor-induced immune response with Febe van Maldegem, PhD. In addition, Roberto Spada will offer a glimpse into the future of #spatialbiology, highlighting new automation, acquisition modes and analysis solutions.Hear about a recent study of KRAS-G12C inhibition in lung cancer outlining the mechanisms that restrain immunotherapy sensitivity in non-responsive tumors. The team used multiplex Imaging Mass Cytometry™ to explore spatial patterns in the tumor microenvironment, providing leads for novel therapeutic combinations in the treatment of non-small-cell lung cancer.Save your seat: https://lnkd.in/gfCTjcb2

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“By categorizing these tumors, we can start to tailor and think about improving or personalizing those therapies.”Have a minute? Take a look at this quick read in The Scientist about new findings, published inCancer Discovery, that could help researchers understand why some tumors respond to immunotherapies better than others. Using Imaging Mass Cytometry™, the team characterized thearchitectural arrangement of immune cellsin human lung tumors... https://lnkd.in/gCyNfp9i#immunecells #lungcancer #tumorcells #spatialbiology

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Michael Egholm, President and CEO of Standard BioTools™,will participate in a fireside chatat the Jefferies Global Healthcare Conferenceon Wednesday, June 5,at 2:30 pm ET. During this Q&A session, he will be discussing our growth strategy delivering superior data quality and insights using high-plex solutions for translational and clinical research. This year’s gathering will bring together 3,000 leading executives to address near-and long-term investment opportunities as well as the current trends driving healthcare in the U.S. and internationally. #JefferiesHealthcare. This sessionwill be webcast live and available on our Investor Relations Events pageathttps://lnkd.in/gUwtQQbF.A recording will be archived and available on our Investor Relations homepage atinvestors.standardbio.com.

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